Erectile Dysfunction
What is Impotence?
Impotence (or Erectile Dysfunction) is defined as the "inability to obtain and/or maintain an erection sufficient for satisfactory sexual intercourse" and can be an embarrassing problem for men of all different ages. People affected by this condition are usually aged 40 or over, but even some men in their early 20s or 30s suffer from impotence problems.
Causes of Impotence
Impotence is often considered to be a psychological or mental problem, but this is a myth. In reality, medical impotence is more often caused by physiological factors and less so by psychological ones. Sometimes impotence can seriously impede male sexual relations and can result in low self-esteem. In these cases, erectile dysfunction affects men more in a psychological than in a physical way.
Physiological Causes of Impotence People who suffer from diabetes, hypertension (high blood pressure), high cholesterol, prostate problems or hormonal imbalance, who have suffered heart attacks, strokes or abdominal injury or who have undergone surgery, are much more at risk of impotence. People who habitually smoke, drink alcohol or take drugs are also more likely to develop signs of erectile dysfunction.
Psychological Causes of Impotence People who experience abnormally high pressure at work, stress, anxiety, depression, tension, insomnia or other sleeping disorders or side effects of certain medication, may suffer from impotence. In these cases, the occurance of impotence is often related to the modern day lifestyles and living habits of men.
Medical Solution for Impotence
Impotence at a primary level, also known as Low Degree Impotence, can be treated simply by improving one’s life style and work habits without any medical intervention. But in more serious cases, it will be necessary to consult a doctor and follow their advice, usually by taking prescription medication. Viagra, Cialis and Levitra are three highly effective ED drugs which can treat more serious cases of impotence.
Generic Viagra (Sildenafil Citrate)
Generic Viagra (Sildenafil Citrate) is manufactured by Pfizer and was the first ever erectile dysfunction drug to appear on the market. Its active ingredient - Sildenafil Citrate - increases the blood flow to the penis during sexual stimulation, which makes it easier to obtain and maintain an erection. Generic Viagra (Sildenafil Citrate) takes effect approximately one hour after consumption and then works for four hours.
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Generic Cialis (Tadalafil)
The ED medication that was most recently launched is Generic Cialis (Tadalafil), an impotence drug manufactured by Lilly ICOS LLC. Generic Cialis (Tadalafil) takes effect faster than Viagra and remains in the body for longer - up to 36 hrs. Its main component, Tadalafil, widens the blood vessels of the penis, which in turn facilitates and increases the blood flow necessary to obtain and maintain an erection.

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Generic Levitra (Vardenafil)
Generic Levitra (Vardenafil) is the third main erectile dysfunction drug. It is available in smaller doses than Viagra and works a lot faster. The effects of Generic Levitra (Vardenafil) are felt as quickly as 30 minutes after administration. Generic Levitra (Vardenafil) belongs to the category of inhibitors and works by relaxing the muscles of the penis. This enables an increase in blood flow and makes it easier to obtain and maintain an erection. Levitra was developed and is being marketed through a joint effort by GlaxoSmithKline (GSK) and Bayer.
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Urinary Health
Benign Prostatic Hyperplasia (BPH)
Benign Prostatic Hyperplasia or BPH is a common condition in middle-aged or elderly men, characterized by an increase in size of the prostate. When the prostate becomes sufficiently large, it can cause partial or even complete obstruction of the urethra, which significantly interferes with urine flow. This leads to symptoms of urinary hesitancy, frequent urination, dysuria or painful urination, an increased risk of urinary tract infections and urinary retention.
Causes of BPH
In cases of BPH, the prostate grows larger due to an increase in the number of cells (hyperplasia). The precise reason for this increase is unknown, but there are a few theories. Researchers believe a variety of factors may be involved in the development of BPH, including androgens (male hormones), estrogens, growth factors and other cell signaling pathways.
There are also strong indications of the involvement of DHT (Dihydrotestosterone) in the development of BPH. DHT is a strong male sex hormone, which is formed in various places of the body through the reaction of testosterone with the type II 5-alpha reductase enzyme. When DHT is formed in the prostate, it binds itself to existing cells, changes them and makes them grow.
Medical Solution for BPH
Other than making serious life style changes or undergoing surgery, BPH can be treated by means of medication. The two main types of drugs used for this treatment are alpha blockers and 5α-reductase inhibitors.
Alpha blockers are the most common choice for initial therapy in the USA and Europe. They can treat BPH by relaxing smooth muscle in the prostate and the bladder neck and thus decreasing the blockage of urine flow. Medication of this kind includes Doxazosin, Terazosin, Alfuzosin, Tamsulosin, and Silodosin.
5α-reductase inhibitors, such as Finasteride and Dutasteride are another treatment option. These medications inhibit 5α-reductase and this in turn inhibits the production of DHT. Effects may take longer to appear than alpha blockers, but they persist for many years. When used together with alpha blockers, a reduction of BPH progression has been noted in patients with larger prostates, leading to a significant improvement of acute urinary retention.
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